Print E-mail
Volume 50, Number 5, October 2017

The effect of immunization with pneumococcal conjugated vaccines on Streptococcus pneumoniae resistance patterns in acute otitis media 

Tal Marom, Elad Avraham, Udi Cinamon, Sharon Ovnat Tamir


Corresponding author:

Sharon Ovat Tamir, Corresponding author. Department of Otolaryngology-Head and Neck Surgery, Edith Wolfson Medical Center, Tel Aviv University Sackler School of Medicine, P.O. Box 5, 58100 Holon, Israel. 


Background and purpose: 

Following the introduction of 7- and 13-pneumococcal conjugate vaccines (PCVs) in Israel, we demonstrated that within Streptococcus pneumoniae (Sp) positive middle ear cultures, obtained from young children with severe acute otitis media (AOM) episodes, there were more penicillin-susceptible and less multi-drug resistant Sp isolates in PCV immunized children. 


Key words:

acute otitis media, antibiotic resistance, pneumococcal conjugate vaccine, Streptococcus pneumoniae