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Volume 49, Number 3, June 2016

Leclercia adecarboxylata bacteremia in a patient with long-term use of nonsteroidal anti-inflammatory drugs 

Shio-Shin Jean, Wen-Sen Lee, Kuan-Jen Bai, Carlos Lam, Chin-Wang Hsu, Ray-Jade Chen, Po-Ren Hsueh


Corresponding author:

Corresponding author. Po-Ren Hsueh, Departments of Laboratory Medicine and Internal Medicine, National Taiwan University Hospital, Number 7, Chung-Shan South Road, Taipei 100, Taiwan. 


Background and purpose: 

Leclercia adecarboxylata, a ubiquitous Gram-negative bacillus, is generally viewed as an opportunistic pathogen because it is rarely cultured from clinical samples. Although rare, bacteremia due to L. adecarboxylata tends to occur in immunocompromised hosts and patients with systemic comorbidities. Only one case of bacteremia due to L. adecarboxylata has been reported in a previously healthy patient. We describe a male patient with an active peptic ulcer who developed L. adecarboxylata bacteremia after a long-term use of nonsteroidal anti-inflammatory drugs. The abdomen is believed to have been the most probable portal of entry. After appropriate medical management, the patient recovered without sequela. 


Key words:

Bacteremia, Immunocompetent, Leclercia adecarboxylata, Nonsteroidal anti-inflammatory drugs, Peptic ulcer