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Volume 49, Number 3, June 2016

Bacillus cereus septicemia in a patient with acute lymphoblastic leukemia: A case report and review of the literature 

Ya-Ling Chou, Shin-Nan Cheng, Kao-Hsian Hsieh, Chih-Chien Wang, Shyi-Jou Chen, Wen-Tsung Lo


Corresponding author:

Corresponding author. Wen-Tsung Lo, Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Number 325, Cheng-Kung Road, Section 2, Nei-hu 114, Taipei, Taiwan, ROC. 


Background and purpose: 

Bacillus cereus is an aerobic Gram-positive, spore-forming, rod-shaped bacterium that is responsible for foodborne illnesses. We report on a 15-year-old girl with B-cell acute lymphoblastic leukemia, who fell into a somnolent state after presenting with a 12-hour history of fever, muscle soreness, myalgia in both calves, sore throat, and vomiting. Fulminant septicemic syndrome caused by B. cereus was finally identified. The aim of this work is the introduction of B. cereus as a differential diagnosis of sepsis in patients with acute leukemia in induction chemotherapy, to prevent delayed treatment. 


Key words:

Acute leukemia, Bacillus cereus, Fulminant septicemic syndrome