Tigecycline salvage therapy for necrotizing fasciitis caused by Vibrio vulnificus: Case report in a child
Yu-San Lin, Min-Hsiang Hung, Chi-Chung Chen, Kuo-Feng Huang, Wen-Chien Ko, Hung-Jen Tang
Corresponding author. Department of Medicine, Chi Mei Medical Center, 901 Chung Hwa Road, Yung Kang City, Tainan 710, Taiwan.
Background and purpose:
Necrotizing fasciitis caused by Vibrio vulnificus is rarely reported in children. We describe a 12-year-old immunocompetent boy with necrotizing fasciitis caused by V. vulnificus. He was cured by radical and serial debridement and salvage therapy with intravenous cefpirome plus tigecycline. The in vitro antibacterial activity of combination regimens and a literature review of pediatric V. vulnificus infection are described.
Child, Necrotizing fasciitis, Tigecycline, Vibrio vulnificus