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Volume 49, Number 1, February 2016

Severe macrolide-resistant Mycoplasma pneumoniae pneumonia associated with macrolide failure 

Kai-Ning Cheong, Susan S. Chiu, Betsy Wai-Ka Chan, Kelvin Kai-Wang To, Eunice Lai-Yin Chan, Pak-Leung Ho


Corresponding author:

Pak-Leung Ho
Corresponding author. Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Pokfulam, Hong Kong Special Administrative Region, China. 


Background and purpose: 

We investigated differences in outcomes between 68 children hospitalized with macrolide-sensitive Mycoplasma pneumoniae pneumonia (MSMP group) and 25 children hospitalized with macrolide-resistant M. pneumoniae pneumonia (MRMP group). In the MRMP group, 19 children received macrolides and clinical failure occurred in six of which five had pneumonia progression during therapy. 


Key words:

atypical pneumonia, empyema, macrolides