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Volume 49, Number 1, February 2016

Aggregatibacter aphrophilus brain abscess secondary to primary tooth extraction: Case report and literature review 

Sofia Maraki, Ioannis S. Papadakis, Efkleidis Chronakis, Dimitrios Panagopoulos, Antonis Vakis


Corresponding author:

Sofia Maraki
Corresponding author. Department of Clinical Microbiology, Parasitology, Zoonoses and Geographical Medicine, University Hospital of Heraklion, 71 110 Heraklion, Crete, Greece. 


Background and purpose: 

We report on a rare case of Aggregatibacter aphrophilus brain abscess of odontogenic origin in a 6-year-old previously healthy boy, who had close contact with a pet dog. The poodle was the most likely source of the infecting organism, which subsequently colonized the patient's oral cavity. The abscess was surgically removed and he recovered completely after prolonged antibiotic treatment with meropenem. We also review the relevant medical literature on A. aphrophilus pediatric brain abscesses. 


Key words:

Aggregatibacter aphrophilus, Brain abscess, Canine transmission, Odontogenic origin