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Volume 48, Number 6, December 2015

Fatal pneumonia and empyema thoracis caused by imipenem-resistant Nocardia abscessus in a cancer patient 


Chih-Cheng Lai, Hsih-Yeh Tsai, Sheng-Yuan Ruan, Chun-Hsing Liao, Po-Ren Hsueh


Received: November 6, 2012    Revised: December 21, 2012    Accepted: January 22, 2013   

 

Corresponding author:

Po-Ren Hsueh
Correspondence
Corresponding author. Departments of Laboratory Medicine and Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, Taiwan. 



 

Background and purpose: 

We describe a case of pneumonia and empyema thoracis caused by trimethoprim–sulfamethoxazole-susceptible, but imipenem-resistant Nocardia abscessus in a cancer patient. The isolate was confirmed to the species level by 16S rRNA sequencing analysis. The patient did not respond to antibiotic therapy, including ceftriaxone and imipenem, and died of progressing pneumonia and multiple organ failure. 



 

Key words:

Empyema thoracis, Imipenem-resistant, Nocardia abscessus, 16S rRNA sequencing