Breakthrough disseminated cryptococcosis during micafungin therapy
Wen-Sen Lee, Tai-Chin Hsieh, Tsong-Yih Ou, Sing-On Teng, Fu-Lun Chen, Fu-Der Wang
Received: July 26, 2011 Revised: November 26, 2012 Accepted: March 13, 2013
Corresponding author. Division of Infectious Disease, Department of Internal Medicine, Taipei Veterans General Hospital, National Yang-Ming University of Medicine, Number 111, Section 3, Hsing-Long Road, Taipei, Taiwan.
Background and purpose:
Echinocandins are not active against basidiomycetous yeasts, such as Cryptococcus neoformans, Trichosporon, and Rhodotorula species, and zygomycosis. We present a patient with renal failure and candidemia, who developed a breakthrough fungal infection with cryptococcemia and cryptococcuria while receiving micafungin therapy.
Breakthrough fungal infection, Cryptococcosis, Micafungin