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Volume 48, Number 3, June 2015

Pachydermodactyly: Three new cases in Taiwan 


Chen-Kuan Chen, Shyh-Dar Shyur, Szu-Hung Chu, Li-Hsin Huang, Yu-Hsuan Kao, Ling-Chun Liu


Received: November 15, 2011    Revised: September 1, 2012    Accepted: September 13, 2012   

 

Corresponding author:

Shyh-Dar Shyur
Division of Allergy, Immunology, Rheumatology Disease, Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
Correspondence
Corresponding author. 14F-1, 136, MinChuan West Road, Taipei 103, ROC. 



 

Background and purpose: 

Pachydermodactyly (PDD), Greek for thick-skin-finger, is an infrequently recognized benign disorder characterized by painless fusiform swelling of the soft tissues around the proximal interphalangeal joints of the hands. Histopathologic features include increased dermal accumulation of collagen fibers. Young males are predominantly affected. PDD is quite rare with approximately 90 cumulative cases reported worldwide. We report three new cases of PDD in Taiwan, including two female patients. Except for patient 1 having the habit of cracking the knuckles, and patient 2 having a history of patent ductus ateriosus post catheterization, the histories of all three patients were unremarkable. X-ray of bilateral hands revealed no abnormal finding except for soft tissue swelling around proximal interphalangeal joints. Laboratory examinations all showed negative results. No local or systemic treatment was given to these patients to treat PDD, with the exception of non-steroidal anti-inflammatory drugs prescribed to one patient for a short period. Skin care with local irritation avoidance was explained to all three patients. The long-term outcome of PDD was benign. 



 

Key words:

Collagen, Fibroblast, Fibromatosis, Pachydermodactyly, Proximal interphalangeal joint