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Volume 48, Number 1, February 2015

Pseudomonas aeruginosa retro-orbital abscess and cerebritis leading to a diagnosis of interleukin-1 receptor-associated kinase-4 deficiency 

Andrew Rosser, Deborah E. Modha

Received: August 21, 2013       Accepted: November 4, 2013   


Corresponding author:

*Corresponding author. Department of Infection and
Tropical Medicine, Leicester Royal Infirmary,
Infirmary Square, Leicester LE1 5WW, UK.
E-mail address: 


Background and purpose: 

Invasive ocular infections due to Pseudomonas aeruginosa infections are rare. Previous studies have reported cases in immunocompromised hosts,1 patients after surgery (radial keratotomy),2 as well as in neonates.3 Herein, we present the case of a healthy male infant who at 9 months of age presented to the emergency department with a right upper eyelid preseptal cellulitis. He neither had a history of eye trauma nor abnormal family history. On Day 3 after admission, he had worsening inflammation, prompting us to examine him under anesthesia.