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Volume 47, Number 1, February 2014

Efficacy of nasal irrigation in the treatment of acute sinusitis in atopic children

Yun-Hu Wang, Min-Sho Ku, Hai-Lun Sun, Ko-Huang Lue

Received: February 2, 2012    Revised: June 30, 2012    Accepted: August 17, 2012   


Corresponding author:

Ko-Huang Lue, Corresponding author. Division of Allergy, Asthma and Rheumatology, Department of Pediatrics, Chung Shan Medical University Hospital, No. 110, Section 1, Jianguo N. Road, Taichung 40201, Taiwan. 


Background and purpose: 

Nasal irrigation has been used as adjunctive therapy for sinonasal disease but is under-researched in children. The study aim was to evaluate the effectiveness of nasal irrigation with normal saline in the management of acute sinusitis in atopic children. 



We enrolled 60 atopic children with acute sinusitis, of whom 29 received nasal irrigation with normal saline and 31 did not receive nasal irrigation. All participants underwent a nasal peak expiratory flow rate (nPEFR) test, a nasal smear examination, and radiography (Water's projection) and were requested to complete a Pediatric Rhinoconjunctivitis Quality-of-Life Questionnaire (PRQLQ) during the baseline visit. All participants were requested to record symptoms in a daily diary and were followed up at 1-week intervals. A physical examination, nasal smear, and nPEFR were performed at each visit, and all daily diaries were collected. At the final visit (after 3 weeks), the symptom diaries were reviewed and participants were requested to complete the PRQLQ again. nPEFR, radiography, and a nasal smear were also repeated.



There were significant improvements in mean PRQLQ and nPEFR values (p < 0.05) for the irrigation compared to the non-irrigation group. There was no significant difference in radiographic findings between the groups (p > 0.05). The irrigation group recorded significant improvements in eye congestion, rhinorrhea, nasal itching, sneezing, and cough symptoms compared with the non-irrigation group.



Nasal irrigation is an effective adjunctive treatment for acute sinusitis in atopic children.


Key words:

Acute sinusitis, Atopic children, Nasal peak expiratory flow rate, Pediatric Rhinoconjunctivitis Quality-of-Life Questionnaire