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Volume 46, Number 3, June 2013

Plasma-cell type Castleman’s disease of the neck and lymphocyte-depletion Hodgkin lymphoma associated with intestinal intussusception in an AIDS patient 

Chung-Hsu Lai, Jen-Wei Tsai, Jiun-Nong Lin, Pei-Min Hsieh, Hsi-Hsun Lin

Received: July 25, 2011    Revised: December 23, 2011    Accepted: January 10, 2012   


Corresponding author:

Division of Infectious Diseases, Department of Internal Medicine, E-Da Hospital/I-Shou University, Kaohsiung County, Taiwan, ROC
Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan, ROC
Corresponding author. Division of Infectious Diseases, E-Da Hospital/I-Shou University, 1, E-Da Road, Jiau-Shu Village, Yan-Chau District, Kaohsiung City 824, Taiwan, ROC. 


Background and purpose: 

A 36-year-old man was diagnosed with plasma-cell type Castleman’s disease with the presentation of recurrent lymphadenpathy of the neck. HIV infection was not suspected or confirmed until esophageal candidiasis developed one year later. Meanwhile, surgery was performed for intestinal intussusception and obstruction caused by lymphocyte-depletion Hodgkin lymphoma. However, he died of rapidly progressive pneumonia and disseminated intravascular coagulation associated with intracerebral hemorrhage, which occurred 6 months later during the course of chemotherapy. This case suggests that HIV infection should be considered in patients who present with plasma-cell type Castleman’s disease or lymphocyte-depletion Hodgkin lymphoma with extra-nodal involvement in order to conduct appropriate diagnosis and initiate treatment for HIV infection. 


Key words:

AIDS, Castleman’s disease, HIV, Hodgkin lymphoma, Intestinal obstruction