Print E-mail
Volume 44, Number 6, December 2011

Emergence of uncommon emmtypes of streptococcus pyogenes among adult patients in southern Taiwan.

 


Chuan Chiang-Ni, An-Bang Wu, Ching-Chuan Liu, Kow-Ton Chen, Yee-Shin Lin, Woei-Jer Chuang, Hsin-Yi Fang, Jiunn-Jong Wu


Received: November 15, 2010    Revised: November 20, 2010    Accepted: December 31, 2010   

 

Corresponding author:
  • Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
  • Corresponding Author InformationCorresponding author. Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, No. 1, Ta-Hsueh Road, Tainan 70101, Taiwan.


 

Background and purpose: 

Streptococcus pyogenes isolated from adult patients during a 12-year period in southern Taiwan were analyzed to estimate the distribution of emm types and their correlation with disease manifestations and patient age.



 

Methods:

Three hundred thirty-four invasive and noninvasive isolates collected from patients older than 20 years between 1997 and 2008 at National Cheng Kung University Hospital were included for emm typing. A correlation between emm type, disease manifestations, and patient ages was analyzed.



 

Results:

The nine most prevalent types were emm11, emm12, emm4, emm1, Sp9458/VT8, emm81, emm106, emm13, and emm75. Formerly rare emm types, including emm11, emm81, and emm102, emerged dramatically after 2004 in southern Taiwan. Type emm11 was significantly associated with both superficial infections and cellulitis. In addition, types emm13, emm81, and emm106 were more prevalent in patients older than 50 years and significantly associated with specific invasive disease manifestation.



 

Conclusion:

These results suggest new emm types (emm11, emm81, and emm102) of S pyogenes were introduced into the adult population in southern Taiwan after 2004. The rarely reported emm types, including emm13, emm81, and emm106, caused invasive diseases more often in adult patients.



 

Key words:

Adults, emm type, Streptococcus pyogenes, Taiwan