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Volume 44, Number 4, August 2011

Coinfection with Mycobacterium tuberculosis and pandemic H1N1 influenza A virus in a patient with lung cancer

Che-Kim Tan, Chiang-Lian Kao, Jin-Yuan Shih, Li-Na Lee, Chien-Ching Hung, Chih-Cheng Lai, Yu-Tsung Huang, Po-Ren Hsueh

Received: July 3, 2007    Revised: August 28, 2009    Accepted: March 2, 2010   


Corresponding author:

Departments of Laboratory Medicine and Internal Medicine, National Taiwan University Hospital, No. 7,
Chung-Shan South Rd, Taipei 100, Taiwan. E-mail address: (P.-R. Hsueh)


Background and purpose: 

Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus were responsible for bacterial coinfection during previous or 2009 influenza pandemic and were associated with a higher risk of influenza-related morbidity and mortality. Despite tuberculosis (TB) is still a growing problem worldwide, Mycobacterial tuberculosis is rarely a copathogen with influenza. We hereby report a cancer patient with TB and pandemic H1N1 influenza A virus coinfection. Physicians should be aware that TB may present as a coinfection in an immunocompromised patient with 2009 influenza A (H1N1) infection, especially in TB endemic area.


Key words:

Coinfection, Mycobacterium tuberculosis, Pandemic influenza A (H1N1) virus