Nutritional Status and Clinical Characteristics in Children With Juvenile Rheumatoid Arthritis
Shou-Ting Shina, Hsin-Hui Yub, Li-Chieh Wangb, Jyh-Hong Lee, Yu-Tsan Linb, Yao-Hsu Yangb, Bor-Luen Chiang
Received: May 1, 2008 Revised: December 15, 2008 Accepted: April 21, 2009
Department of Pediatrics, National Taiwan University Hospital, 7 Zhongshan South in adult rheumatoid arthritis patients. The body mass index Road, Taipei, Taiwan. (BMI) in men and women are significantly reduced in rheumatoid arthritis patients compared with controls.4
Background and purpose:
The aim of the study was to investigate the clinical characteristics and nutritional status of juvenile rheumatoid arthritis (JRA) in Taiwanese children. METHODS: Fifty-three patients were included in this study. The disease subtype and patient characteristics were recorded. Body mass index (BMI) was determined. Seventy-five healthy age-matched children served as a control group.
Fifty-three patients were included in this study. The disease subtype and patient characteristics were recorded. Body mass index (BMI) was determined. Seventy-five healthy age-matched children served as a control group.
The inflammation parameters, including white blood cell count, platelet count, C-reactive protein, and erythrocyte sedimentation rate, were elevated in the systemic group. The BMI level of the JRA group was significantly lower than the control group (p= 0.006), especially in the male patients (p=0.016) and when the patient age was greater than 4 (p= 0.011). The patients with oligoarticular onset JRA had significantly lower BMI compared with the healthy control group (p=0.012).
Nutritional status is often impaired in patients with JRA. The BMI of the JRA patients was lower than that of age-matched healthy children, especially in the male group, and when disease onset age was greater than 4. In our unselected sample, the most affected disease subtype was oligoarticular onset JRA.
body mass index, juvenile rheumatoid arthritis, nutritional status