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Volume 42, Number 5, October 2009

Rapidly fatal bacteremic pneumonia caused by Klebsiella pneumoniae with K1 hypermucoviscosity phenotype in a previously healthy young man receiving levofloxacin treatment


Tzu-Yi Chuang, Chou-Jui Lin, Chun-Lin Chi, An-Yu Liu, Shih-Wei Lee, T. L. Lin, Jin-Town Wang, Po-Ren Hsueh
Tzu-Yi Chuang, Chou-Jui Lin, Chun-Lin Chi, An-Yu Liu, Shih-Wei Lee, T. L. Lin, Jin-Town Wang, Po-Ren Hsueh Department of Internal Medicine, and Department of Emergency Medicine, Taoyuan General Hospital, Taoyuan; Department of Health, Department of Microbiology, National Taiwan University College of Medicine; Department of Laboratory Medicine, and Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan

Received: October 24, 2008    Revised: October 30, 2010    Accepted: November 5, 2008   

 

Corresponding author:

Po-Ren Hsueh, Departments of Laboratory Medicine and Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Rd., Taipei 100, Taiwan. E-mail: Dr. Po-Ren Hsueh 



 

Background and purpose: 

Rapidly fatal bacteremic Klebsiella pneumoniae pneumonia (BKPP) is commonly encountered in alcoholic and diabetic patients (1-3), but has not been reported in previously healthy young adults. This report is of a previously healthy young adult with atypical presentation of BKPP, septic shock, multiple organ failure, and rapidly fatal outcome despite aggressive treatment, including recombinant human activated protein C (rhAPC; drotrecogin alfa).



 

Key words:

 Bacteremia; Klebsiella pneumoniae; Pneumonia