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Volume 34, Number 1, March 2001

Legionnaires\' disease in a patient with rheumatoid arthritis

Chi-Ching Chang, Chi-Li Chung, Chen-Ling Huang, Fong-Chieh Wang
Department of Internal Medicine, Taipei Medical College, Taiwan, ROC



A 62-year-old male with rheumatoid arthritis (RA) who was taking nonsteroid anti-inflammatory drug for controlling synovitis developed a flare of his arthritis, hepatitis, and pneumonia due to infection with Legionella pneumophila serotype 1. Adult respiratory distress syndrome (ARDS) occurred following the development of pneumonia. After the introduction of erythromycin and ventilator support with positive end expiratory pressure (PEEP), his condition stabilized and he recovered gradually. We suggest that L. pneumophila should be considered early in the differential diagnosis of pneumonia in RA patients due to their immunocompromised status.



J Microbiol Immunol Infect 2001;34:76-78.