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Volume 37, Number 2, April 2004

Mycoplasma pneumoniae infection presenting as neutropenia, thrombocytopenia, and acute hepatitis in a child

Chun-Jung Chen, Chun-Jung Juan, Mu-Ling Hsu, Yuan-Sheng Lai, Shih-Peng Lin, Shin-Nan Cheng
Departments of Pediatrics and Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei; Department of Electrical Engineering, College of Electrical Engineering and Computer Sciences, National Taiwan University, Taipei, Taiwan, ROC

Received: February 14, 2003    Revised: May 8, 2003    Accepted: July 16, 2003   


Corresponding author:

Dr. Shin-Nan Cheng, Department of Pediatrics, Tri-Service General Hospital, No. 325, Cheng-Kung Road, Section 2, Neihu, Taipei, Taiwan 114, ROC. E-mail: This e-mail address is being protected from spam bots, you need JavaScript enabled to view it




Extrapulmonary manifestations of Mycoplasma pneumoniae pneumonia are uncommon and include hematologic, gastrointestinal, musculoskeletal, dermatologic, and neurologic complications. We report a case of serologically-confirmed M. pneumoniae infection complicated by severe neutropenia, thrombocytopenia, and hepatitis. The presence of antiplatelet and antineutrophil antibodies suggested that these autoantibodies caused the cytopenias. The disease had an acute course and the patient recovered after steroid treatment. This case indicates that neutropenia, thrombocytopenia and hepatitis are possible clinical manifestations of M. pneumoniae infection.



Key words:

Acute, hepatitis, Mycoplasma pneumoniae, neutropenia, thrombocytopenia



J Microbiol Immunol Infect 2004;37:128-130.