Mycoplasma pneumoniae infection presenting as neutropenia, thrombocytopenia, and acute hepatitis in a child
Chun-Jung Chen, Chun-Jung Juan, Mu-Ling Hsu, Yuan-Sheng Lai, Shih-Peng Lin, Shin-Nan Cheng
Departments of Pediatrics and Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei; Department of Electrical Engineering, College of Electrical Engineering and Computer Sciences, National Taiwan University, Taipei, Taiwan, ROC
Received: February 14, 2003 Revised: May 8, 2003 Accepted: July 16, 2003
Extrapulmonary manifestations of Mycoplasma pneumoniae pneumonia are uncommon and include hematologic, gastrointestinal, musculoskeletal, dermatologic, and neurologic complications. We report a case of serologically-confirmed M. pneumoniae infection complicated by severe neutropenia, thrombocytopenia, and hepatitis. The presence of antiplatelet and antineutrophil antibodies suggested that these autoantibodies caused the cytopenias. The disease had an acute course and the patient recovered after steroid treatment. This case indicates that neutropenia, thrombocytopenia and hepatitis are possible clinical manifestations of M. pneumoniae infection.
Acute, hepatitis, Mycoplasma pneumoniae, neutropenia, thrombocytopenia
J Microbiol Immunol Infect 2004;37:128-130.