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Volume 41, Number 4, August 2008

Lack of increase in time to blood culture positivity in a patient with persistent methicillin-resistant Staphylococcus aureus bacteremia predicts failure of antimicrobial therapy


Chun-Hsing Liao, Yu-Tsung Huang, Fang-Yeh Chu, Tsui-Hsien Lin, Po-Ren Hsueh
Department of Internal Medicine, Far Eastern Memorial Hospital, Taipei; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei; Department of Laboratory Medicine, Far Eastern Memorial Hospital, Taipei; and Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan

Received: December 4, 2007    Revised: February 1, 2008    Accepted: March 15, 2008   

 

Corresponding author:

Dr. Po-Ren Hsueh, Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, 7, Chung-Shan South Road, 100 Taipei, Taiwan. E-mail: Dr. Po-Ren Hsueh This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
 



 

Methods:

Time to positivity is an available parameter in automated blood culture systems. We report a patient withpersistent methicillin-resistant Staphylococcus aureus bacteremia who received various regimens for treatment of methicillin-resistant S. aureus, and demonstrate that monitoring of the time to positive blood culture might be helpful in the early recognition of treatment failure.



 

Key words:

Bacteremia; Methicillin resistance; Staphylococcus aureus

 



 

J Microbiol Immunol Infect. 2008;41:355-357.