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Volume 41, Number 5, October 2008

Brain abscesses in children: analysis of 20 cases presenting at a medical center


Kai-Liang Kao, Keh-Gong Wu, Chun-Jen Chen, Jionn-Jong Wu, Ren-Bin Tang, Kai-Ping Chang, Tai-Tong Wong
Department of Pediatrics, Taipei Veterans General Hospital and National Yang-Ming University; Department of Pediatrics and Department of Surgery, Service of Neurosurgery, Far Eastern Memorial Hospital; and Department of Neurosurgery, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan

Received: May 12, 2007    Revised: June 1, 2007    Accepted: July 31, 2007   

 

Corresponding author:

Dr Keh-Gong Wu, Department of Pediatrics, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei 112, Taiwan. E-mail: Dr Keh-Gong Wu This e-mail address is being protected from spam bots, you need JavaScript enabled to view it

 



 

Background and purpose: 

Brain abscess is an uncommon intracranial suppuration, especially in children. We reviewed the records of children with brain abscess admitted to Taipei Veterans General Hospital, Taipei, Taiwan, and analyzed data on presenting symptoms, predisposing factors and outcomes.
 



 

Methods:

Information was obtained retrospectively from medical records of children diagnosed with brain abscess. Demographic data, presenting symptoms, predisposing factors, sites of abscess, infectious organisms, treatment regimen, and prognosis were collected and analyzed.
 



 

Results:

Twenty cases of brain abscess within an 11-year period were included in this study. Fever, seizure and focal neurological deficits were the most common presenting symptoms. Cyanotic congenital heart disease (CCHD), present in 35% of patients, was the most common predisposing factor. Staphylococcus aureus was the most common pathogen. Approximately two-thirds of cases followed up had some form of seizure disorder sequelae; such sequelae were more common in patients with the initial presentation of seizure.
 



 

Conclusion:

CCHD was the most common predisposing factor for brain abscess in children, and a high level of seizure disorder sequelae was noted. Children suffering from brain abscess, whose initial presentation reveals seizure, are at increased risk of further seizure disorder.
 



 

Key words:

Brain abscess; Child; Heart defects, congenital; Seizures; Treatment outcome

 



 

J Microbiol Immunol Infect. 2008;41:403-407.